ALPROSTADIL (al PROS ta dil) is a natural protein. It is used to treat neonates with a specific heart defect. This medicine is used for a short time until the condition can be corrected.

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as newborn for selected conditions, precautions do apply.

Side effects that you should report to your doctor or health care professional as soon as possible:

•allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

•breathing problems

•changes in blood pressure

•changes in heart rate

•extremely irritable

•fever

•flushing

•seizures

•trouble passing urine or change in the amount of urine

•unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

•diarrhea

•irritation at site where injected

This drug is given in a hospital or clinic and will not be stored at home.

They need to know if you have any of these conditions:

•bleeding problems

•breathing problems

•stomach blockage

•an unusual or allergic reaction to alprostadil or other medicines, foods, dyes, or preservatives

•pregnant or trying to get pregnant

•breast-feeding

•medicines for blood pressure

This does not apply.

Your condition will be monitored carefully while you are receiving this medicine.