Amphetamine; Dextroamphetamine Tablets

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    Amphetamine Salts Oral tablet

    What is this medication?

    AMPHETAMINE; DEXTROAMPHETAMINE (am FET a meen; dex troe am FET a meen) treats attention-deficit hyperactivity disorder (ADHD). It works by improving focus and reducing impulsive behavior. It may also be used to treat narcolepsy. It works by promoting wakefulness. It belongs to a group of medications called stimulants.

    This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

    How should I use this medication?

    Take this medication by mouth. Take it as directed on the prescription label at the same time every day. You can take it with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop.

    A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

    Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 3 years for selected conditions, precautions do apply.

    Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

    What side effects may I notice from receiving this medication?

    Side effects that you should report to your care team as soon as possible:

    • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
    • Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
    • Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
    • Increase in blood pressure
    • Irritability, confusion, fast or irregular heartbeat, muscle stiffness, twitching muscles, sweating, high fever, seizure, chills, vomiting, diarrhea, which may be signs of serotonin syndrome
    • Mood and behavior changes—anxiety, nervousness, confusion, hallucinations, irritability, hostility, thoughts of suicide or self-harm, worsening mood, feelings of depression
    • Prolonged or painful erection
    • Raynaud syndrome—cool, numb, or painful fingers or toes that may change color from pale, to blue, to red
    • Seizures
    • Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision

    Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

    • Dry mouth
    • Headache
    • Loss of appetite with weight loss
    • Nausea
    • Stomach pain
    • Trouble sleeping
    This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Where should I keep my medication?

    Keep out of the reach of children and pets. This medication can be abused. Keep it in a safe place to protect it from theft. Do not share it with anyone. It is only for you. Selling or giving away this medication is dangerous and against the law.

    Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light and moisture. Keep container tightly closed. Get rid of any unused medication after the expiration date.

    This medication may cause harm and death if it is taken by other adults, children, or pets. It is important to get rid of the medication as soon as you no longer need it, or it is expired. You can do this in two ways:

    • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
    • If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, take the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
    NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

    What should I tell my care team before I take this medication?

    They need to know if you have any of these conditions:

    • Anxiety or panic attacks
    • Circulation problems in fingers or toes (Raynaud syndrome)
    • Glaucoma
    • Heart attack
    • Heart disease
    • High blood pressure
    • Kidney disease
    • Liver disease
    • Mental health conditions
    • Seizures
    • Stroke
    • Substance use disorder
    • Suicidal thoughts, plans, or attempt by you or a family member
    • Thyroid disease
    • Tourette syndrome
    • An unusual or allergic reaction to dextroamphetamine, other medications, foods, dyes, or preservatives
    • Pregnant or trying to get pregnant
    • Breastfeeding

    What may interact with this medication?

    Do not take this medication with any of the following:

    • Linezolid
    • MAOIs, such as Marplan, Nardil, and Parnate
    • Methylene blue

    This medication may also interact with the following:

    • Acetazolamide
    • Alcohol
    • Ascorbic acid
    • Certain medications for depression, anxiety, or other mental health conditions
    • Certain medications for migraines, such as sumatriptan
    • Guanethidine
    • Opioids
    • Reserpine
    • Sodium bicarbonate
    • St. John's wort
    • Thiazide diuretics, such as chlorothiazide
    • Tryptophan
    This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

    What if I miss a dose?

    If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

    What should I watch for while using this medication?

    Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

    This medication requires a new prescription from your care team every time it is filled at the pharmacy.

    This medication can be abused and cause your brain and body to depend on it after high doses or long term use. Your care team will assess your risk and monitor you closely during treatment.

    Long term use of this medication may cause your brain and body to depend on it. You may be able to take breaks from this medication during weekends, holidays, or summer vacations. Talk to your care team about what works for you. If your care team wants you to stop this medication permanently, the dose may be slowly lowered over time to reduce the risk of side effects.

    Tell your care team if this medication loses its effects, or if you feel you need to take more than the prescribed amount. Do not change your dose without talking to your care team.

    Do not take this medication close to bedtime. It may prevent you from sleeping.

    Loss of appetite is common when starting this medication. Eating small, frequent meals or snacks can help. Talk to your care team if appetite loss persists. Children should have height and weight checked often while taking this medication.

    Tell your care team right away if you notice unexplained wounds on your fingers and toes while taking this medication. You should also tell your care team if you experience numbness or pain, changes in the skin color, or sensitivity to temperature in your fingers or toes.

    Contact your care team right away if you have an erection that lasts longer than 4 hours or if it becomes painful. This may be a sign of a serious problem and must be treated right away to prevent permanent damage.

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