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Canagliflozin Oral tablet

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Mar.27.2024

Canagliflozin Tablets

What is this medication?

CANAGLIFLOZIN (KAN a gli FLOE zin) treats type 2 diabetes. It works by helping your kidneys remove sugar (glucose) from your blood through the urine, which decreases your blood sugar. It can also be used to lower the risk of heart attack, stroke, kidney disease, and hospitalization for heart failure in people with type 2 diabetes.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

How should I use this medication?

Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Take it before the first meal of the day. Take your dose at the same time each day. Do not take more often than directed. Do not stop taking except on your care team's advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Dehydration—increased thirst, dry mouth, feeling faint or lightheaded, headache, dark yellow or brown urine
Diabetic ketoacidosis (DKA)—increased thirst or amount of urine, dry mouth, fatigue, fruity odor to breath, trouble breathing, stomach pain, nausea, vomiting
Genital yeast infection—redness, swelling, pain, or itchiness, odor, thick or lumpy discharge
Infection or redness, swelling, tenderness, or pain in the genitals, or area from the genitals to the back of the rectum
New pain or tenderness, change in skin color, sores or ulcers, infection of the leg or foot
Urinary tract infection (UTI)—burning when passing urine, passing frequent small amounts of urine, bloody or cloudy urine, pain in the lower back or sides

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

Change in diet, eating less
Changes to your insulin dose
Dehydration
Diet low in salt
Frequently drink alcohol
Having surgery
History of amputation
History of diabetic ketoacidosis (DKA)
History of foot sores caused by diabetes
History of genital infections
History of pancreatitis or pancreas problems
History of urinary tract infections (UTI)
Kidney disease
Liver disease
Nerve condition that causes pain, tingling, or numbness in the hands or feet
Peripheral vascular disease, narrowing of the blood vessels
Serious infection
Trouble passing urine
Type 1 diabetes
An unusual or allergic reaction to canagliflozin, other medications, foods, dyes, or preservatives
Pregnant or trying to get pregnant
Breastfeeding

What may interact with this medication?

Do not take this medication with any of the following:

Gatifloxacin

This medication may also interact with the following:

Alcohol
Certain medications for blood pressure, heart disease
Digoxin
Diuretics
Insulin
Lithium
Nateglinide
Phenobarbital
Phenytoin
Repaglinide
Rifampin
Ritonavir
Sulfonylureas, such as glimepiride, glipizide, glyburide

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

You may need blood work done while you are taking this medication. Your care team will monitor your HbA1C (A1C). This test shows what your average blood sugar (glucose) level was over the past 2 to 3 months.

Know the symptoms of low blood sugar and know how to treat it. Always carry a source of quick sugar with you. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink if your blood sugar is too low and you are unable to care for yourself. Get medical help at once.

Tell your care team if you have high blood sugar. Your medication dose may change if your body is under stress. Some types of stress that may affect your blood sugar include fever, infection, and surgery.

This medication may increase the risk of diabetic ketoacidosis (DKA), a serious condition in which high ketone levels make your blood too acidic. Your care team may ask you to check for ketones in your urine or blood while you are taking this medication. If you develop nausea, vomiting, stomach pain, unusual weakness or fatigue, or trouble breathing, stop taking this medication and call your care team right away.

Check with your care team if you have severe diarrhea, nausea, and vomiting, or if you sweat a lot. The loss of too much body fluid may make it dangerous for you to take this medication.

Wear a medical ID bracelet or chain. Carry a card that describes your condition. List the medications and doses you take on the card.