Factor IX Complex Injection

FACTOR IX COMPLEX (FAK ter nine COM plecks) prevents and treats bleeding episodes in people with hemophilia B, a condition caused by low levels of blood clotting factor IX. It works by increasing factor IX levels in your body. This helps your blood clot normally, which reduces bleeding.

This medication is infused into a vein. It is usually given by your care team in a hospital or clinic setting. It may also be given at home.

If you get this medication at home, you will be taught how to prepare and give it. Take it as directed on the prescription label.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.

Talk to your care team about the use of this medication in children. While it may be given to children for selected conditions, precautions do apply.

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Blood clot—pain, swelling, or warmth in the leg, shortness of breath, chest pain

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Fatigue
• Flushing
• Headache
• Nausea
• Pain, redness, or irritation at injection site

Keep out of the reach of children and pets.

Your care team will tell you how to store this medication. Get rid of any unused medication as instructed or after the expiration date, whichever is first.

To get rid of medications that are no longer needed or have expired:

• Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.

They need to know if you have any of these conditions:

• Have had blood clots
• Having or recent surgery
• Heart disease
• Liver disease
• An unusual or allergic reaction to factor IX, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

• Aminocaproic acid
• Tranexamic acid

It is important not to miss your dose. Talk to your care team about what to do if you miss a dose.

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

You may need blood work done while you are taking this medication.

Some blood factor products are made from donated human blood. There is a small risk that they may contain bacteria or viruses, such as hepatitis or HIV. All products are processed to kill most bacteria and viruses. Talk to your care team if you have questions about the risk of infection.

Avoid taking medications that contain aspirin, ibuprofen, or naproxen. These medications may increase your risk of bleeding. Your care team may recommend acetaminophen for mild pain or fever.

Wear a medical ID bracelet or chain. Carry a card that describes your condition. List the medications and doses you take on the card.