Fluconazole Tablets

FLUCONAZOLE (floo KON na zole) prevents and treats fungal or yeast infections. It belongs to a group of medications called antifungals. It will not prevent or treat colds, the flu, or infections caused by bacteria or viruses.

Take this medication by mouth. Take it as directed on the prescription label at the same time every day. You can take it with or without food. If it upsets your stomach, take it with food. Take all of this medication unless your care team tells you to stop it early. Keep taking it even if you think you are better.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as newborns for selected conditions, precautions do apply.

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
• Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
• Low adrenal gland function—nausea, vomiting, loss of appetite, unusual weakness or fatigue, dizziness
• Rash, fever, and swollen lymph nodes
• Redness, blistering, peeling, or loosening of the skin, including inside the mouth
• Seizures

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Change in taste
• Diarrhea
• Dizziness
• Headache
• Nausea
• Stomach pain

Keep out of the reach of children.

Store at room temperature below 30 degrees C (86 degrees F). Throw away any medication after the expiration date.

They need to know if you have any of these conditions:

• Irregular heartbeat or rhythm
• Kidney disease
• Liver disease
• Low levels of potassium in the blood
• An unusual or allergic reaction to fluconazole, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

Do not take this medication with any of the following:

• Adagrasib
• Flibanserin
• Lomitapide
• Lonafarnib
• Other medications that cause heart rhythm changes
• Triazolam

This medication may also interact with the following:

• Abrocitinib
• Certain antibiotics, such as rifabutin or rifampin
• Certain antivirals for HIV or hepatitis
• Certain medications for blood pressure, heart disease, irregular heartbeat
• Certain medications for cholesterol, such as atorvastatin, lovastatin, simvastatin
• Certain medications for depression, such as amitriptyline or nortriptyline
• Certain medications for diabetes, such as glipizide or glyburide
• Certain medications for seizures, such as carbamazepine or phenytoin
• Certain medications that treat or prevent blood clots, such as warfarin
• Certain opioid medications for pain, such as alfentanil, fentanyl, methadone
• Cyclophosphamide
• Cyclosporine
• Ibrutinib
• Lemborexant
• Midazolam
• NSAIDS, medications for pain and inflammation, such as ibuprofen or naproxen
• Olaparib
• Sirolimus
• Steroid medications, such as prednisone
• Tacrolimus
• Theophylline
• Tofacitinib
• Tolvaptan
• Vinblastine
• Vincristine
• Vitamin A
• Voriconazole

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Visit your care team for regular checkups. If you are taking this medication for a long time you may need blood work. Tell your care team if your symptoms do not improve. Some fungal infections need many weeks or months of treatment to cure.

Alcohol can increase possible damage to your liver. Avoid alcoholic drinks.

If you have a vaginal infection, do not have sex until you have finished your treatment. You can wear a sanitary napkin. Do not use tampons. Wear freshly washed cotton, not synthetic, panties.