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Complications and Prognosis
Screening and Prevention
Admission may be required if bleeding is not readily controlled with outpatient or emergency department care; length of stay for invasive procedures (or childbirth) may be increased
Prophylaxis (periprocedural) and treatment include replacement of factor XI and/or use of antifibrinolytic drugs (ie, tranexamic acid, aminocaproic acid) r5
Determining the need for prophylaxis is problematic r8
There are few published guidelines with specific recommendations for management of hemophilia C; UK Haemophilia Centre Doctors' Organisation offers the following: r11r17
Menorrhagia can be controlled with antifibrinolytic agents; an intrauterine device or oral contraceptives may be considered r4
World Federation of Hemophilia recommends immunization against hepatitis A and B for all patients with hemophilia r18
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