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HISTRELIN (his TREL in) treats a condition that causes early puberty. It works by decreasing levels of the hormones estrogen and testosterone in the body. This slows or stops signs of puberty while you are taking this medication.
This medication is placed under the skin of your arm by your care team in a clinic or office. After the implant is placed, keep the insertion site clean and dry for 24 hours. Avoid heavy lifting and strenuous exercise for 7 days after implant insertion. The surgical strips over the site should be allowed to fall off on their own over several days. The implant must be removed after 12 months. At this time, a new implant may be inserted to continue therapy.
A special MedGuide will be given to you before each treatment. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. While this drug may be prescribed for children as young as 2 years for selected conditions, precautions do apply.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
This medication is given in a hospital or clinic. It will not be stored at home.
They need to know if you have any of these conditions:
This does not apply. After 1 year, the implant will have to be removed. If you need to continue this medication, the implant will be replaced at that time.
Visit your care team for regular checks on your progress. During the first few weeks, the symptoms of puberty may get worse, but then will start to get better as treatment is continued. Check with your care team if they do not start to get better after several weeks.
Rarely, the implant can be expelled from the body through the original incision site. You may notice the implant being expelled, or rarely, the implant may be expelled without your noticing it. If you believe the implant has been expelled from your body, call your care team.
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