Lansoprazole Granules for Suspension

LANSOPRAZOLE (lan SOE pra zole) treats heartburn, stomach ulcers, reflux disease, or other conditions that cause too much stomach acid. It works by reducing the amount of acid in the stomach. It belongs to a group of medications called PPIs.

Take this medication by mouth. Follow the directions on the prescription label. First, mix the contents (granules) of the packets with 2 tablespoonfuls (30 ml) of water to form a strawberry-flavored suspension. Do not crush or chew the granules before mixing. Stir well and drink the liquid mixture immediately. If any material from the suspension remains after drinking, add more water, stir, and drink immediately. Do not take this medication with other liquids or foods. It is best to take this medication at least 30 to 60 minutes before you eat any food. Take your doses at regular intervals. Do not take your medication more often than directed.

Talk to your care team about the use of this medication in children. Special care may be needed.

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
• Low magnesium level—muscle pain or cramps, unusual weakness or fatigue, fast or irregular heartbeat, tremors
• Low vitamin B12 level—pain, tingling, or numbness in the hands or feet, muscle weakness, dizziness, confusion, difficulty concentrating
• Rash on cheeks or arms that gets worse in the sun
• Redness, blistering, peeling, or loosening of the skin, including inside the mouth
• Severe diarrhea, fever
• Unusual bruising or bleeding

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Diarrhea
• Dry mouth
• Gas
• Headache
• Nausea

Keep out of the reach of children and pets.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medication after the expiration date.

They need to know if you have any of these conditions:

• Liver disease
• Low levels of calcium, magnesium, or potassium in the blood
• Lupus
• An unusual or allergic reaction to lansoprazole, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

Do not take this medication with any of the following:

• Atazanavir
• Nelfinavir

This medication may also interact with the following:

• Ampicillin
• Delavirdine
• Digoxin
• Diuretics
• Iron salts
• Itraconazole, ketoconazole, voriconazole, or other prescription medications for fungus or yeast infections
• Sucralfate
• Theophylline
• Warfarin

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

It can take several days before your stomach pain gets better. Check with your care team if your condition does not start to get better, or if it gets worse.

Do not treat diarrhea with over the counter products. Contact your care team if you have diarrhea that lasts more than 2 days or if it is severe and watery.

You may need blood work done while you are taking this medication.

Using this medication for a long time may weaken your bones. The risk of bone fractures may be increased. Talk to your care team about your bone health.

Using this medication for a long time may cause growths (polyps) in the stomach. They usually don't cause any symptoms. They are usually not cancerous. Contact your care team if you notice pain or tenderness when you press your stomach, have nausea, or see bloody or black, tar-like stools.

This medication may cause a decrease in vitamin B12. You should make sure that you get enough vitamin B12 while you are taking this medication. Discuss the foods you eat and the vitamins you take with your care team.