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Most patients with monkeypox have mild, self-limited disease, which can be managed with supportive care alone r18
Potential management options depend on affected systems and specific disease manifestations or complications; options may include the following: r41
Consider antiviral treatment for the following patients after consultation with state health authorities or CDC through the Emergency Operations Center (telephone, 1-770-488-7100): r18
Currently there are no treatments approved specifically for monkeypox virus infection, but several antiviral agents originally developed for treatment of smallpox and other viral infections may be considered and obtained from the Strategic National Stockpile upon request from state health authorities after consultation with CDC; efficacy data for these agents is lacking owing to infeasibility of human smallpox experimentation r17r18