Multisystem inflammatory syndrome in children (MIS-C)
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Complications and Prognosis
Screening and Prevention
By definition, patients with MIS-C or MIS-A require hospitalization r2r13
Consider admission for patients under investigation for MIS in the following circumstances: r33
Outpatient evaluation may be appropriate for well-appearing children with normal vital signs provided close clinical follow-up is assured r33
General treatment overview
Treatment of MIS-A is based on extrapolation from other conditions including MIS-C r15r37r56
Treatment of MIS-N is similarly extrapolated from MIS-C therapy r16r17
Initial stabilization and urgent management priorities d9
Antiviral therapy considerations
Extracorporeal membrane oxygenation is required in some patients with severe disease refractory to other medical management
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