Doxylamine; Vitamin B6 Delayed- or Extended-Release Tablets

DOXYLAMINE; VITAMIN B6 (dox IL a meen; VAHY tuh min B6) treats nausea and vomiting during pregnancy. It works by blocking substances in your body that cause nausea and vomiting. It is a combination of an antihistamine and vitamin B6.

Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the tablets whole. Take it on an empty stomach. Do not use it more often than directed. Keep taking it unless your care team tells you to stop.

Talk to your care team about the use of this medication in children. Special care may be needed.

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
• Trouble passing urine

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Confusion
• Constipation
• Dizziness
• Drowsiness
• Dry mouth

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep bottle tightly closed and protect from moisture. Do not remove desiccant canister from bottle. Throw away any unused medication after the expiration date.

They need to know if you have any of these conditions:

• Glaucoma
• Liver disease
• Pain or trouble passing urine
• Prostate disease
• Stomach ulcers, other stomach or intestine problems
• An unusual or allergic reaction to doxylamine, pyridoxine (vitamin B6), other medications, foods, dyes, or preservatives
• Breast-feeding

• Alcohol
• Atropine
• Antihistamines for allergy, cough and cold
• Certain medications for bladder problems, such as oxybutynin, tolterodine
• Certain medications for stomach problems, such as dicyclomine, hyoscyamine
• Certain medications for travel sickness, such as scopolamine
• Certain medications for Parkinson's disease, such as benztropine, trihexyphenidyl
• Ipratropium
• MAOIs, such as Marplan, Nardil, and Parnate

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. See your care team right away if you get a high fever or have problems breathing.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy and drinking plenty of water may help. Contact your care team if the problem does not go away or is severe.

This medication may cause dry eyes and blurred vision. If you wear contact lenses, you may feel some discomfort. Lubricating eye drops may help. See your care team if the problem does not go away or is severe.

This medication may cause false positive urine tests for certain medications like methadone, opiates, and PCP.

This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.