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Mifepristone Oral tablet [Pregnancy Termination]
What is this medication?
MIFEPRISTONE (mi FE pri stone) is used to end an early pregnancy. It works by decreasing levels of the hormone progesterone in the body, which stops the pregnancy from progressing.
How should I use this medication?
Take this medication by mouth. Take it as directed. You will take this medication along with other medications. Talk to your care team about any questions you have.
A special MedGuide will be given to you. Be sure to read this information carefully.
Talk to your care team about the use of this medication in children. Special care may be needed.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Heavy vaginal bleeding
- High fever
- Stomach pain, unusual weakness or fatigue, nausea, vomiting, diarrhea, or fever that lasts longer than expected
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
- Chills
- Dizziness
- Headache
- Stomach cramping
Where should I keep my medication?
Keep out of reach of children and pets.
Store at 25 degrees C (77 degrees F). Get rid of any unused medication after the expiration date.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
- Bleeding disorder
- Cannot easily get emergency medical help in the 2 weeks after you take this medication
- Cannot return for follow-up appointments in 1 to 2 weeks after you take this medication
- Ectopic or tubal pregnancy
- Have an intrauterine device (IUD)
- It has been more than 70 days (10 weeks) since your last menstrual period began
- Low adrenal gland function
- Porphyria
- Take medications that prevent or treat blood clots
- Taking steroids, such as dexamethasone or prednisone
- An unusual or allergic reaction to mifepristone, misoprostol, other medications, foods, dyes, or preservatives
- Breastfeeding
What may interact with this medication?
Do not take this medication with any of the following:
- Certain medications that prevent or treat blood clots, such as enoxaparin, dalteparin, apixaban, dabigatran, or rivaroxaban
- Regularly take steroid medications, such as budesonide, dexamethasone, methylprednisolone, prednisolone, prednisone, or cortisone
This medication may also interact with the following:
- Certain antibiotics, such as clarithromycin or erythromycin
- Certain antivirals for HIV or hepatitis
- Certain medications for fungal infections, such as ketoconazole, itraconazole, or posaconazole
- Certain medications for seizures, such as carbamazepine, phenytoin, or phenobarbital
- Certain medications that prevent or treat blood clots, such as warfarin
- Grapefruit juice
- Rifampin
- St. John's wort
What if I miss a dose?
This does not apply. This medication is not for regular use.
What should I watch for while using this medication?
For your safety, you must visit your care team as directed after taking this medication. Report any unusual effects to your care team. This medication can cause birth defects. You will need surgery if this medication fails to cause a full loss of pregnancy.
After you take this medication, some vaginal bleeding is normal. Heavy bleeding may be a sign that something is wrong. If you soak through 2 thick full-size sanitary pads each hour for 2 hours, get medical help right away.
