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Complications and Prognosis
Screening and Prevention
Sepsis requires inpatient acute care for monitoring, IV antimicrobial therapy, and supportive care
Initial treatment often occurs in the emergency department and is continued in the inpatient setting; treatment should proceed rapidly regardless of setting r4
Treatment includes immediate stabilization, fluid resuscitation, initiation of antimicrobials, hemodynamic support, and source control r4
Additional treatment required after initial management in select cases of sepsis
Once the causative pathogen is identified, de-escalate antimicrobial treatment, based on culture and sensitivity results, and continue for a duration appropriate to the diagnosis (7-10 days in most cases) r23
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