Taliglucerase Alfa Injection

TALIGLUCERASE ALFA (tal i GLOO ser ace alfa) treats Gaucher disease. It works by replacing an enzyme normally made by the body, which reduces the buildup fatty substances (lipids) in the spleen, liver, bones, and other tissues. This decreases symptoms.

This medication is infused into a vein. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. While it may be given to children as young as 4 years for selected conditions, precautions do apply.

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Infusion reactions—chest pain, shortness of breath or trouble breathing, feeling faint or lightheaded

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Dizziness
• Fatigue
• Headache
• Joint pain
• Nausea
• Vomiting

This medication is given in a hospital or clinic. It will not be stored at home.

They need to know if you have any of these conditions:

• An unusual or allergic reaction to taliglucerase alfa, other medications, foods, dyes, or preservatives
• Pregnant or are trying to get pregnant
• Breastfeeding

Interactions are not expected.

Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

This medication can cause serious allergic reactions. To reduce the risk, your care team may give you other medications to take before receiving this one. Follow the direction from your care team.