Trifluridine Eye Solution

TRIFLURIDINE (trye FLURE i deen) helps manage eye infections caused by viruses. It belongs to a group of medications called antivirals. It does not kill the virus and it may still be possible to spread the virus to others. It will not treat infections caused by bacteria.

This medication is only for use in the eye. Follow the directions on the prescription label. Wash hands before and after use. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the dropper or tube to your eye, fingertips, or other surfaces. Squeeze the prescribed number of drops into the pouch. Close the eye gently to spread the drops. Do not use your medication more often than directed. Finish the full course of medication prescribed by your care team even if you think your condition is better. Do not stop using except on the advice of your care team.

Talk to your care team about the use of this medication in children. Special care may be needed.

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• New or worsening eye pain, redness, irritation, or discharge

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Burning or stinging of the eyes after use
• Eye irritation or itching

Keep out of the reach of children and pets.

Store in the refrigerator. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

• Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

They need to know if you have any of these conditions:

• An unusual or allergic reaction to trifluridine, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

Interactions are not expected. Do not use any other eye products without talking to your care team.

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

This medication can cause permanent damage to the cornea (the front of the eye) if used for a long time. Do not use this medication for more than 21 days.