Phentermine; Topiramate Oral Extended-release Capsules
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Phentermine; Topiramate (FEN ter meen; Toe PYRE a mate) promotes weight loss. It may also be used to maintain weight loss. It works by decreasing appetite. Changes to diet and exercise are often combined with this medication.
Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Do not crush or chew. This medication is usually taken with or without food once per day in the morning. Avoid taking this medication in the evening. It may interfere with sleep. Take your doses at regular intervals. Do not take your medication more often than directed.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 12 years for selected conditions, precautions do apply.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Keep out of the reach of children and pets. This medication can be abused. Keep it in a safe place to protect it from theft. Do not share it with anyone. It is only for you. Selling or giving away this medication is dangerous and against the law.
Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Protect from moisture. Keep the container tightly closed.
This medication may cause harm and death if it is taken by other adults, children, or pets. It is important to get rid of the medication as soon as you no longer need it, or if it is expired. You can do this in two ways:
They need to know if you have any of these conditions:
Do not take this medication with any of the following:
This medication may also interact with the following:
If you miss a dose, skip it. Take your next dose at the normal time. Do not take extra or 2 doses at the same time to make up for the missed dose.
Visit your care team for regular checks on your progress.
Do not stop taking this medication except on your care team's advice. You may develop a severe reaction. Your care team will tell you how much medication to take.
Do not take this medication close to bedtime. It may prevent you from sleeping.
Avoid extreme heat. This medication can cause you to sweat less than normal. Your body temperature could increase to dangerous levels, which may lead to heat stroke.
You should drink plenty of fluids while taking this medication. If you have had kidney stones in the past, this will help to reduce your chances of forming kidney stones.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may increase dizziness and drowsiness. Avoid alcoholic drinks.
This medication may affect blood sugar levels. Ask your care team if changes in diet or medications are needed if you have diabetes.
Check with your care team if you have severe diarrhea, nausea, and vomiting, or if you sweat a lot. The loss of too much body fluid may make it dangerous for you to take this medication.
Tell your care team right away if you have any change in your eyesight.
Watch for new or worsening thoughts of suicide or depression. This includes sudden changes in mood, behaviors, or thoughts. These changes can happen at any time but are more common in the beginning of treatment or after a change in dose. Call your care team right away if you experience these thoughts or worsening depression.
This medication may cause serious skin reactions. They can happen weeks to months after starting the medication. Contact your care team right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.
Birth control may not work properly while you are taking this medication. Talk to your care team about using an extra method of birth control.
Tell your care team if you wish to become pregnant or think you might be pregnant. There is a potential for serious side effects and harm to an unborn child. Losing weight while pregnant is not advised and may cause harm to the unborn child. Talk to your care team for more information.
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