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Jun.08.2021

Semaglutide Solution for injection [Weight Management]

What is this medicine?

SEMAGLUTIDE (Sem a GLOO tide) is used to help people lose weight and maintain weight loss. It is used with a reduced-calorie diet and exercise.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

How should I use this medicine?

This medicine is injected under the skin. You will be taught how to prepare and give it. Take it as directed on the prescription label. It is given once every week (every 7 days). Keep taking it unless your health care provider tells you to stop.

It is important that you put your used needles and pens in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or health care provider to get one.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

This medicine comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medicine. Read the information carefully. Talk to your pharmacist or health care provider if you have questions.

Talk to your health care provider about the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • changes in vision
  • fast heartbeat
  • gallbladder problems (fever, upper belly pain, yellowing of the eyes or skin, clay-colored stool)
  • kidney injury (trouble passing urine or change in the amount of urine)
  • low blood sugar (feeling anxious; confusion; dizziness; increased hunger; unusually weak or tired; increased sweating; shakiness; cold, clammy skin; irritable; headache; blurred vision; loss of consciousness)
  • lump or swelling on the neck
  • pancreatitis (stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting)
  • suicidal thoughts, mood changes
  • trouble breathing
  • trouble swallowing

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • constipation
  • diarrhea
  • headache
  • heartburn (burning feeling in chest, often after eating or when lying down)
  • nausea
  • pain, redness, or irritation at site where injected
  • passing gas
  • upset stomach
  • vomiting
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children and pets.

Refrigeration (preferred): Store in the refrigerator. Do not freeze. Keep this medicine in the original container until you are ready to take it. Get rid of any unused medicine after the expiration date.

Room temperature: If needed, prior to cap removal, the pen can be stored at room temperature for up to 28 days. Protect from light. If it is stored at room temperature, get rid of any unused medicine after 28 days or after it expires, whichever is first.

It is important to get rid of the medicine as soon as you no longer need it or it is expired. You can do this in two ways:

  • Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medicine, follow the directions in the MedGuide.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • endocrine tumors (MEN 2) or if someone in your family had these tumors
  • eye disease, vision problems
  • gallbladder disease
  • history of depression or mental health disease
  • history of pancreatitis
  • kidney disease
  • stomach or intestine problems
  • suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
  • thyroid cancer or if someone in your family had thyroid cancer
  • an unusual or allergic reaction to semaglutide, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

What may interact with this medicine?

  • insulin and other medicines for diabetes
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What if I miss a dose?

If you miss a dose and the next scheduled dose is more than 2 days away, take the missed dose as soon as possible. If you miss a dose and the next scheduled dose is less than 2 days away, do not take the missed dose. Take the next dose at your regular time. Do not take double or extra doses. If you miss your dose for 2 weeks or more, take the next dose at your regular time or call your health care provider to talk about how to restart this medicine.

What should I watch for while using this medicine?

Visit your health care provider for regular checks on your progress. It may be some time before you see the benefit from this medicine.

Drink plenty of fluids while taking this medicine. Check with your health care provider if you have severe diarrhea, nausea, and vomiting, or if you sweat a lot. The loss of too much body fluid may make it dangerous for you to take this medicine.

This medicine may affect blood sugar levels. Ask your health care provider if changes in diet or medicines are needed if you have diabetes.

If you or your family notice any changes in your behavior, such as new or worsening depression, thoughts of harming yourself, anxiety, other unusual or disturbing thoughts, or memory loss, call your health care provider right away.

Women should inform their health care provider if they wish to become pregnant or think they might be pregnant. Losing weight while pregnant is not advised and may cause harm to the unborn child. Talk to your health care provider for more information.

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